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Just over the northern border of the US, patients with the same devastating genetic condition—cystic fibrosis—are living an average of 10 years longer , researchers reported Monday in the Annals of Internal Medicine. After adjusting for differences among patients’ overall health, disease severity, and clinical factors, a team of American and Canadian researchers found that cystic fibrosis patients’ median age of survival is 50.9 years in Canada and 40.6 years in the US. Though the study did not fully assess the causes for the “significant survival gap,” the researchers noted that better access to lung transplants and healthcare in general appeared to play a role. In fact, when comparing Canadian patients who have universal, government-provided health insurance with US patients who have private insurance, the researchers found no difference in the risk of death. But, US patients with continuous or intermittent Medicare or Medicaid or with no insurance at all had 36 to 77 percent higher risks of death than their Canadian counterparts. “Although we cannot draw definitive causal inferences from these analyses, the observed differences raise the question of whether a disparity exists in access to therapeutic approaches or health care delivery such that hypotheses may be generated for further investigation,” the authors conclude. And further investigations are indeed warranted, researchers say. “A ten-year difference… that’s lots of years spent with your child or not, having fun with your friends, living your life,” epidemiologist Kevin Gorey of the University of Windsor, who was not involved with the study, told STAT . “That’s a huge, huge human tragedy.” Previous estimates and assessments have pegged the survival rate of cystic fibrosis patients in developing countries from 41.5 to 50 years. But directly comparing survival data between countries is tricky because they may have different methods for tracking and recording patient health data.

For the original version including any supplementary images or video, visit https://arstechnica.com/science/2017/03/cystic-fibrosis-patients-live-10-years-longer-in-canada-than-in-the-us/

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